A Sioux Falls woman has been sentenced to 20 years in federal prison after being convicted of distributing fentanyl that resulted in the death of another woman. The sentencing took place on March 2, 2026, before U.S. District Judge Karen E. Schreier.
Anastasia Muggins, 33, received the sentence along with five years of supervised release and was ordered to pay a $100 special assessment to the Federal Crime Victims Fund. She was indicted by a federal grand jury in May 2025 and pleaded guilty on December 11, 2025.
The case stemmed from the death of Sheila Eastman, who was found dead at her residence in Sioux Falls on December 15, 2024. Eastman was an enrolled member of the Flandreau Santee Sioux Tribe and born in Flandreau. The coroner determined that she died from fentanyl toxicity. According to investigators, Muggins distributed approximately 0.1 grams of fentanyl powder to Eastman, which led to her death.
“On December 15, 2025, the one-year anniversary of the death of Sheila Eastman from fentanyl poisoning, this Administration issued an Executive Order officially designating fentanyl as a weapon of mass destruction,” said U.S. Attorney Parsons. “As this case tragically shows, illicit fentanyl is much closer to a chemical weapon than a simple narcotic. Just two milligrams, an almost undetectable trace amount equivalent to 10 to 15 grains of table salt, is a lethal dose. Hundreds of thousands of Americans like Sheila have been killed by the fentanyl smuggled into this country from China and the Mexican drug cartels. We are committed to doing everything we can to put an end to the death and misery these chemical weapons continue to cause.”
The investigation was conducted by the Sioux Falls Police Department and the Drug Enforcement Administration. Assistant U.S. Attorney Mark Hodges prosecuted the case.
Muggins was immediately remanded into custody following sentencing.
